DLSS:
DLSS support is coming later this year for DirectX 12 mode.
Developer Q&A Live on January 26 - Flight Simulator Blog

Developer Q&A Twitch Series: January 26th, 2022:
00:00 Introductions
02:11 2021 Recap
05:07 World Update 7 Trailer
07:50 Local Legend 2
09:15 Ellise from Orbx
15:18 New Partner - Fernando / Carenado
20:40 World Update 8
23:10 Roadmap Update
23:38 Seb presentation - Sim Improvements 2022
42:37 Feedback Snapshot
59:01 Complex Airliners / PMDG
53:25 Live Weather
57:52 Xbox 3rd party aircraft
01:02:44 Dx12 Improvements
01:04:45 Open Q&A